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Schizophrenia GABAergic receptors

Despite the preponderance of data correlating the dopamine D2 receptor with schizophrenia, alternative sites in the brain (serotonergic, adrenergic, glutamatergic, and GABAergic) are also being investigated to explain the actions of atypical neuroleptics. [Pg.212]

The NMDA hypothesis, called the glutamatergic dysfunction hypothesis, of schizophrenia is based on the action of glutamate on NMDA receptors on GABAergic, serotonergic, and noradrenergic neurons that inhibit two major excitatory pathways in the retrosplenial cortical neurons. (Coyle, 1996). [Pg.5]

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GABAergic

Receptors schizophrenia

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