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Schizophrenia amphetamine-induced dopamine release

For decades researchers have looked at whether intoxication with certain drugs could mimic the signs and symptoms of schizophrenia. Amphetamines increase dopamine release and can induce some positive symptoms like paranoia. Lysergic acid diethylamide (LSD) affects 5-HT receptors but tends to induce visual perception changes and not frank hallucinations. Phencyclidine (PCP), however, induces a state in healthy controls that seems very similar to schizophrenia. This includes thought disorder and negative symptoms... [Pg.514]

Kegeles LS, Abi-Dargham A, Zea-Ponce Y, Rodenhiser-Hill J, Mann JJ, et al. 2000. Modulation of amphetamine-induced striatal dopamine release by ketamine in humans Implications for schizophrenia. Biol Psychiatry 48 627-640. [Pg.82]

See other pages where Schizophrenia amphetamine-induced dopamine release is mentioned: [Pg.62]    [Pg.71]    [Pg.66]    [Pg.143]    [Pg.374]    [Pg.214]    [Pg.410]    [Pg.33]   
See also in sourсe #XX -- [ Pg.43 , Pg.43 ]



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