Scanning the AMP Binding Site of FBPase

2 Scanning Results vs. Experimental Relative Binding Affinities 

Similarly, differences for the binding affinity of AMP for the AMP binding site of wild-type FBPase vs. mutant FBPase were calculated and compared with experimental data derived from the ratio of the corresponding IC50s. The calculated results generated from the scan were compared with the experimentally-determined relative binding affinities and reported in our earlier communication.13 

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