Sarcomelicope simplicifolia

Sarcomelicope simplicifolia (Endl.) Hartley ssp. Whian Whian, NSW B s [20]... 

Acronycine (1.) is a natural alkaloid which was first isolated in 1948 from the bark of a small Australian Rutaceous tree, Acronychia baueri Schott (1). Since that time, the status of this plant within the Rutaceae family has been revised several times, in the course of successive taxonomic studies (2-5). It is now widely accepted that the plant belongs to the genus Sarcomelicope and should be named Sarcomelicope simplicifolia (Endl.) Hartley ssp. simplicifolia (4). 

Acronycine epoxide 61 was isolated in minute amounts from Sarcomelicope agyrophylla Guill. and from Sarcomelicope simplicifolia (Endl.) Hartley ssp. neo-scotica (P.S. Green) Hartley (68). This compound should be considered as a biogenetic intermediate between acronycine itself and the cis and frans-dihydrodiols 48. and in Sarcomelicope species. It is a highly unstable compound whose reactivity most probably explains the difficulties encountered by us (72) and by others (73, 74) in attempts towards its synthesis. Reisch et al. finally succeeded in synthesizing in 14 % yield by treatment of acronycine with dimethyldioxirane in the presence of potassium carbonate (75). 

Acronycidine I 4,5,7,8-tetraOMe Acronychia baueri [42, 44], Bauerella simplicifolia ssp. neo-scotica [44], Medicosma subsessilis [38], Melicope foreana [42], Sarcomelicope leiocarpa [19], S. megistophylla [29]... 

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