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Sarcoidosis Complicating Type 1 Interferon Therapy

Sarcoidosis Complicating Type 1 Interferon Therapy [Pg.209]

Sarcoidosis is a rare complication of type 1 interferons (IFNs) (IFN-a or IFN-p) used to treat viral hepatitis and diverse autoimmune and malignant disorders (28,149-154). Type 1 IFNs evoke a Thl lymphocyte bias and amplify granulomatous inflammation (151,152). Most cases resolve following withdrawal of rIFN-a or dose reduction (149,155), but CSs are required in some patients (152,156). [Pg.209]

XXIII. Sarcoidosis Complicating Type 1 Interferon Therapy... [Pg.209]

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