Sarcococca pruniformis

A histochemical investigation also established the presence of alkaloids in Pachysandra, Sarcococca, and Simmondsia (190). The alkaloids found in Sarcococca and Pachysandra are simple pregnane derivatives lacking the alkyl substitution at C-4 and C-14. The alkaloids isolated from Sarcococca pruniformis Lindley show close similarity in structure to alkaloids typical of pregnane-type alkaloids of Apocynaceae some of them were found in both families. 

Key to letters a. Pachysandra terminalis Sieb. et Zucc. b. Sarcococca pruniformis Lindl. See Table I. 

Saracodine, an alkaloid isolated from Sarcococca pruniformis, and believed to be 3lS-dimethylamino-20a-methylacetamido-5a-pregnane, is, however, shown to be different from epipachysamine-A (see Section 5). 

Alkaloid C from Sarcococca pruniformis has been identified as 3a-methoxy-20a-dimethylaminopregn-5-ene (43). Emde degradation of (43) followed by catalytic hydrogenation afforded 3a-methoxy-5a-pregnane (44), identical with a sample prepared from 5a-pregnan-3-one.34... 

An alkaloid, salignine, has been isolated from Sarcococca saligna (synonymous with S. pruniformis). Later work has shown that it is identical with sara-codine. ... 

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