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Saquinavir structure-based design

Figure 28-26 Saquinavir (Fortovase, Invjrase), 15, was th first HIV-1 protease inhibitor designed with structure-based CADD methods to receive FDA approval. Mere saquinavir is shown inside the binding cavity of HIV-1. Figure 28-26 Saquinavir (Fortovase, Invjrase), 15, was th first HIV-1 protease inhibitor designed with structure-based CADD methods to receive FDA approval. Mere saquinavir is shown inside the binding cavity of HIV-1.
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See also in sourсe #XX -- [ Pg.435 , Pg.436 , Pg.440 ]

See also in sourсe #XX -- [ Pg.435 , Pg.436 , Pg.440 ]



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Design Bases

Design structures

Structure based design

Structure designable

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