Salmonella enterica sv. Typhimurium

Low concentrations of organic acids are not effective against Salmonella enterica sv. Typhimurium attached to broiler carcasses (Lillard et al., 1987 Tamblyn and Conner, 1994), and application could result in induction of tolerance, which in turn would have an impact on the virulence of a pathogenic invasive organism (Hill, O Driscoll, and Booth, 1995). 

Some organic acids have no inhibitory effect on microorganisms for example, gluconic acid is a highly polar molecule, and is unable to penetrate the cell membrane of E. coli 0157 H7 (Bjornsdottir, Breidt, Jr., and McFeeters, 2006). A tolerance response in Salmonella enterica sv. Typhimurium, induced by lactic acid, will, however, induce sensitivity to hydrogen peroxide (Greenacre et al., 2006). 

Table 9.1 Genes Involved in Increased Acid Tolerance in Salmonella enterica sv. typhimurium Cells Not Adapted to Low pH...

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