Salicylates in children

Studies suggest that the use of salicylates (especially aspirin) maybe involved in the development of Reye s syndrome in children with chickenpox or influenza. This rare but life-threatening disorder is characterized by vomiting and lethargy, progressing to coma. Therefore, use of salicylates in children with chickenpox, fever, or flulikesymptomsisnot recommended. Acetaminophen is recommended for the management of symptoms associated with these disorders... 

Despite our lack of understanding of the syndrome, the decision taken in many countries to advise against the use of salicylates in children under 12 made an impact, in terms of a falling incidence of Reye s syndrome (SEDA-16, 96 SEDA-17, 97). 

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