Rose-Drago Method for NMR Spectroscopy

In this section, the way to apply the original Rose-Drago method for UV/vis spectroscopy to NMR titration data is described, especially for host-guest systems on fast exchange. [Pg.39]

When the host-guest complexation equilibrium has a very slow exchange rate compared with the NMR time scale, the concentration of the complex is expressed as follows (a = 1 in Eq. (2.53)). [Pg.39]

When the host-guest complexation equilibrium has a very fast exchange rate [Pg.39]

Here we carried out the substitution using following definitions (2.58)-(2.62). [Pg.40]

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