RING REARRANGEMENT METATHESIS RRM A NEW CONCEPT IN PIPERIDINE AND PYRROLIDINE SYNTHESIS

RING REARRANGEMENT METATHESIS (RRM) - A NEW CONCEPT IN PIPERIDINE AND PYRROLIDINE SYNTHESIS 

Institutfiir Chemie Technische Universitat Berlin Berlin, Germany 

Nitrogen based heterocycles are present in an array natural products, thousands of which have been mentioned in clinical or preclinical studies.1 Thus, the synthesis of piperidine-2 and pyrrolidine-3 derivatives have attracted much attention from the modem day organic chemists. Of particular interest are strategies that lead to chiral heterocyclic derivatives.4 

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