Atrial fibrillation rimonabant

Cardiovascular Atrial fibrillation has been attributed to rimonabant in two cases [114 ]. 

A man who took rimonabant for 5 weeks developed palpitation, fatigue, and exertional dyspnea. He had atrial fibrillation with a ventricular rate of 98-135/minute. No other cause of atrial fibrillation was found and rimonabant was withdrawn. After 2 weeks his rhythm had reverted to sinus rhythm. The patient refused re-challenge and 9 months later was still in sinus rhythm. 

After taking rimonabant for 3 weeks a man developed dizziness, palpitation, and exertional dyspnea. He had atrial fibrillation, for which no other causes were found. Rimonabant was withdrawn and 10 days later the rhythm had reverted to sinus rhythm with first-degree atrioventricular block. 

Cocco G, Chu D. Rimonabant may induce atrial fibrillation. BMJ 2009 338 bl061. 

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See also in sourсe #XX -- [ ]

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