Riboflavin radioactive studies

All studies of the mechanism of riboflavin synthesis employing radioactive tracers, and the isolation of possible precursors in the biogenesis of the vitamin, have been carried out with the highly flaviogenic ascomycetes, Aahbya goaaypii or Eremothedum aahbyii. 

The remarkable similarity between the chemical structure and the mode of bio thesis of parts of the purine and riboflavin molecules has been extended to the pterins. The studies of Weygand and Waldschmidt (7d) have demonstrated the incorporation of radioactive formate and glycine into leucopterin positions analogous to those in riboflavin and purines. These relationships have been summarized in Fig. 2. 

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