Rhodopsin schematic drawing

Fig. 5.1 Schematic drawing of membrane association modes of peptides A Integral membrane proteins (1) major fd coat protein gpVIII of bacteriophage Ml 3 (pdb lfdm), anchored by an 18-residue trans-membrane hydrophobic helix (2) bovine rhodopsin, a 7 trans-membrane domain (G-protein-coupled) receptor (pdb lf88) (3) ion channel peptaibol Chrysospermin C (pdb lee7), and B Peripheral membrane proteins (1) neuro-...

Figure 23-40 (A) Diagram of a vertebrate rod cell. From Abrahamson and Fager.446 (B) Electron micrograph of a longitudinal section of the outer segment of a retinal rod of a rat. There are 600-2000 discs per rod and 2 x 104 and 8 x 10s rhodopsin molecules per disc. Courtesy of John E. Dowling. (C) Enlarged section from Dratz and Hargrave.451 (D) Schematic drawing of rhodopsin. The two a helices in the front have been partly cut away to reveal the 11-c/s retinal in protonated Schiff base linkage to lysine 296. From Nathans.448 Courtesy of Jeremy Nathans.

Fig. 4.5 Schematic drawing of ground- and excited-state potential surfaces along the 11 -ene torsional coordinates of the chromophore of rhodopsin (A), 8-membered rhodopsin (B), 7-membered rhodopsin (C) and 5-membered rhodopsin (D). This figure is modified from Mizukami et al. [40].

Fig. 6 Comparison of retinal protonated Schiff base chemical shifts in rhodopsin different photocycle states. The chemical structure of retinal chromophore in 11-cw (a) and all-trans configuration (b). Chemical shifts of the retinal atoms in ground state, and Batho-, Meta I, and Meta II intermediate states (c) and a schematic drawing of the retinal binding pocket containing all residues within 4 A to the retinal and Lys296 (d). The chemical shifts are adapted from the following references [146-148] (black) [14] (blue) [149-151] (green) and [17, 145] (red), (d) is adapted from [188] with permission from the Elsevier B.V...

---