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Rheumatoid arthritis pharmacologic therapy

Rheumatoid arthritis and osteoarthritis represent two distinct forms of joint disease that can produce devastating effects on the structure and function of synovial joints. Fortunately, management of these conditions has improved substantially through advancements in drug therapy. Rheumatoid arthritis can be treated pharmacologically with NSAIDs, glucocorticoids, and various DMARDs. NSAIDs, including aspirin, repre-... [Pg.232]

Furst DE. Practical clinical pharmacology and drug interactions of low-dose methotrexate therapy in rheumatoid arthritis. Br J Rheumatol 1995 34(suppl 2) 20-25. [Pg.412]

The PFR has been observed in compounds with pharmacological activity possessing aromatic ester or amide moieties. Benorylate, employed in rheumatoid arthritis therapy, is obtained by esterification of paracetamol with aspirin. Its irradiation leads to PFR with initial cleavage of the central C—O bond to yield 5-acetamido-2 -acetoxy-2-hydroxybenzophenone, which undo-goes transacetylation to 5 -acetamido-2 -acetoxy-2-hydroxybenzophenone (Scheme 31.19) [180]. [Pg.902]

See other pages where Rheumatoid arthritis pharmacologic therapy is mentioned: [Pg.282]    [Pg.84]    [Pg.389]    [Pg.13]    [Pg.255]    [Pg.217]    [Pg.228]    [Pg.229]    [Pg.71]    [Pg.1129]    [Pg.723]    [Pg.17]    [Pg.305]    [Pg.99]    [Pg.335]    [Pg.149]    [Pg.99]   
See also in sourсe #XX -- [ Pg.33 , Pg.41 ]

See also in sourсe #XX -- [ Pg.33 , Pg.41 ]



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