Rhamnulose kinase

Mg2+ binds directly to the phosphate oxygen atoms and through a water molecule to the carboxylate group. Since Mg2+ prefers an octahedral coordination sphere, it requires a water structure different from that observed in holo rhamnulose kinase. 

Grueninger, D. and Schultz, G.E. (2006) Structure and reaction mechanism of L-rhamnulose kinase from Eschericia coli, J. Mol. Biol., 359, 787-797. 

Grueninger, D., Schultz, G. E. (2006). Structure and Reaction Mechanism of L-Rhamnulose Kinase from Eschericia coU. Journal of... 

Several rare ketose 1-phosphates have been obtained by use of L-rhamnulose kinase on the corresponding ketoses which were, in turn, available by isomerization of the appropriate 2R- or 25-aldoses (D-ribose, L-lyxose, L-mannose, L-talose, D-glucose, D-allose, L-rhamnose, L-fucose) with L-rhamnose- or L-fucose-isomerase, respectively. P-L-Fucose 1-phosphate and the thermodynamically less stable p-anomer of GDP-fucose were accessible by use of enzymatic processes. A new, simple, chemical preparation of rhamnulose 1-phosphate from L-rhamnose is outlined in Scheme 5. ... 

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