Rhabdomyolysis, statin-induced

CoUidge TA, Razvi S, Nolan C, Whittle M, Stirling C, Russell AJ, Mann AC, Deighan CJ. Severe statin-induced rhabdomyolysis mimicking Guillain-Barr6 syndrome in four patients with diabetes mellitus treated with fusidic acid. Diabet Med 2010 27(6) 696-700. 

Sochman J, Podzimkova M. Not all statins are alike induced rhabdomyolysis on changing from one statin to another one. Int J Cardiol 2005 99(l) 145-6. 

Drug interactions mediated by CYP3A inhibition can be severe e.g., nephrotoxicity induced by cyclosporine and tacrolimus and rhabdomyolysis resulting from increased levels of statins). Whenever an inhibitor of the CYP3A isoforms is administered, the clinician must be cognizant of the potential for serious interactions with drugs metabolized by CYP3A. 

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