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Retrograde degeneration

A few OPs have been shown to cause OPIDN, a retrograde degeneration of long and large nerve fibers in the spinal cord and peripheral nerves of humans and experimental animals. Some OPs, such as GB, chlorpyrifos, and isofenphos, require very high doses to be acutely neuropathic (WHO 1986 Lotti 1991). Inhibition of approximately 70% or more of the carboxylesterase NTE often is associated with the disorder (WHO 1986 Lotti 1991). Onset of OPIDN is usually 10 days to several weeks after exposure. It is not clear whether OPIDN can occur after long-term exposure to low concentrations of OPs. [Pg.315]

Sorensen JC, Dalmau I, Zimmer J, Finsen B (1996) Microglial reactions to retrograde degeneration of tracer-identified thalamic neurons after frontal sensorimotor cortex lesions in adult rats. Exp Brain Res 112 203—212. [Pg.106]

Kohmura, E., Yuguchi, T., Yamada, K., Sakaguchi, T., and Hayakawa, T., Recombinant basic fibroblast growth factor spares thalamic neurons from retrograde degeneration after ablation of the somatosensory cortex in rats, Restor. Neurol. Neurosci., 6, 309, 1994. [Pg.213]

Leong CC, Syed NI and Lorscheider FL (2001) Retrograde degeneration of neurite membrane structural integrity of nerve growth cones following in vitro exposure to mercury. Neuroreport 12 733-737. [Pg.995]

ACh histochemistry and ChAT immunohisto-chemistry in NBM of AD brains show marked reductions, corresponding to cell loss of about 75%. In cortical target areas, there is also a cholinergic pathology, which may provoke the cholinergic deficit in NBM by retrograde degeneration (Perry, E.K., 1986 Perry, R.H., 1986). [Pg.436]

Berger, K., Przedborski, S. and Cadet, J.L. (1991) Retrograde degeneration of nigrostriatal neurons by intrastriatal 6-hydroxydopamine injection in rats. Brain Res. Bull. 26 301-307. [Pg.481]

Tobimatsu, S., Celesia, G.G., Cone, S. and Gujrati, M. 1989. Electroretinograms to checkerboard pattern reversal in cats physiological characteristics and effect of retrograde degeneration of ganglion cells. Electroenc. Clin. Neurophvs. 73 341-352. [Pg.26]

See other pages where Retrograde degeneration is mentioned: [Pg.388]    [Pg.25]    [Pg.496]    [Pg.133]    [Pg.3]    [Pg.254]    [Pg.67]    [Pg.178]    [Pg.391]    [Pg.36]    [Pg.178]    [Pg.391]    [Pg.141]    [Pg.165]    [Pg.174]    [Pg.176]    [Pg.152]    [Pg.303]    [Pg.382]    [Pg.299]    [Pg.237]    [Pg.43]    [Pg.759]    [Pg.313]   
See also in sourсe #XX -- [ Pg.3 , Pg.254 ]

See also in sourсe #XX -- [ Pg.313 ]



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Retrograde

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