Retinol steady-state level

Since RBP synthesis rate remains normal in retinol-deficient rats, whereas RBP secretion from the liver is blocked in these animals, this study suggests that the RBP degradation rate in the liver must be increased sufficiently in the deficient rats to maintain the elevated steady-state levels of RBP seen in their livers. No information is available about the mechanisms that may be involved in RBP catabolism in the liver or about their possible regulation. 

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