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Retinoids aromatic amines

CYP1B1 (chromosome 5) has been linked to primary congenital glaucoma. CYP1B1 is not regularly expressed in liver but is often found in various kinds of tumours. It metabolizes retinoids and many aromatic amines and PAHs to potentially carcinogenic products. [Pg.925]

The modulation of mutagenicity of aromatic amines in Salmonella is not a result of (a) PCB treatment of rats, or the presence of residual PCB s in liver preparations, (b) vagaries of the Salmonella plate test, or (c) the effect of retinoids upon bacterial viability. [Pg.345]

Similar effects were observed with the synthetic retinoid 13-cis-retinoic acid, while 3-carotene was without effect in modulating the mutagenicity of aromatic amines in Salmonella. [Pg.345]

See other pages where Retinoids aromatic amines is mentioned: [Pg.338]    [Pg.87]    [Pg.143]   
See also in sourсe #XX -- [ Pg.340 ]



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