Results and Monomer Selection

At the time, there were limited options available to optimize the scoring options. 

It is now possible to scale the effect of the individual FieldPoint types, incorporate shape matching, and use constraints none of these options were applied in this study. 

The array was synthesized with 20 monomers selected from the inspection of the Cresset results. The chemists, to complete the array, included an additional selection of 13 monomers. These included certain groups of particular interest to the team, and other examples selected due to their pharmacophoric features of an aromatic ring and an H-bond acceptor. 

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