Respiratory toxins

Li, L. and Holian, A., Acrolein A respiratory toxin that suppresses pulmonary host defense, Rev. Environ. Health. 13, 1-2, 99, 1998. 

The acetylation of a precursor to the natural respiratory toxin ( )-anatoxin-a was best achieved under the Weinreb protocol as depicted in equation (10). Other methods which relied on organocuprate or Grignard addition to thioacetates were totally unsuccessful. A proton-transfer side reaction consumed up... 

The toxic effects of single chemicals on the respiratory system have been fairly well characterized and are listed in numerous places as described earlier in Section 13.2. Though there is no one list of all respiratory toxins, the Scorecard list contains an extensive list of these and includes references for further investigation. 

Voggu, L., Schlag, S., Biswas, R., Rosenstein, R., Rausch, C. and Gotz, F. (2006) Microevolution of cytochrome bd oxidase in Staphylococci and its implication in resistance to respiratory toxins release by Psuedomonas. J. Bacteriol. 188(23), 8079-8086. 

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