Respiration, effect

The schematic below shows that in this dynamic system PAN could affect the synthetic process (site 1), the enzyme itself (site 2), or the degradation process (site 3). If the site of attack were site 2, the synthetic process might compensate for degradation of the enzyme by producing more. If the enzyme activity were measured as a function of time after exposure, there would be first a decrease and then recovery of activity. (Such a response has been observed for the effect of ozone on respiration.) Effects at site 3 would show first an increase in activity and en, if the system were regulated, a decline to normal, as the synthetic process slowed down. Effects at site 1 would cause a decrease in activity commensurate with the rate of enzyme degradation. 

Hodous, T.K. (1989) Workplace measurement of respirator effects using respiratory inductive plethysmography, Am Ind Hyg Assoc J, 50(7) 372-378. 

Respiration Effects, Glyphosate has been reported to uncouple oxidative phosphorylation in plant (103) and mammalian... 

CFR1910.134(k)(l)(iii) 4.4.2.3 How to use the respirator effectively in emergency situations, including situations in which the respirator malfunctions ... 

Continuing respirator effectiveness, (i) Appropriate surveillance shall be maintained of work area conditions and degree of employee exposure or stress. When there is a change in work area conditions ordegree o f employee exposure or stress that may affect respirator effectiveness, the employer shall reevaluate the continued effectiveness of the respirator. 

How to use the respirator effectively in emergency situations, including situations in which the respirator malfunctions. 

Through an oxidation process, silver ions block respiration, effectively choking the microbe, but having no toxic effect on human cells in vivo [19-21]. 

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