Resolution of Enantiomers by Solid State NMR

An interesting method for distinguishing enantiomers and racemates has been proposed by Tekely and coworkers [47] for the determination of enantiomers in P-chiral oxazaphosphorine derivatives (Fig. 3.2.18). 

The pulse sequence used by these authors is ODESSA (one-dimensional exchange spectroscopy by sideband alternation) [48], The experiment is based on the fact that intermolecular distances between chemically equivalent nuclei differ significantly in racemates and enantiomers according to slight but substantial 

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