Resin sections method

Han SS, Kim MK. An improved method for double-isotope and double-emulsion radioautography using epoxy resin sections. Stain Technol 1972 47 291-296. 

Peptide a-oxo acids, a-oxo esters, and a-oxoamides are also potent inhibitors of cysteine and serine proteases. Oxidation of peptide a-substituted carboxylic acid derivatives provides a general route to these compounds (Section 15.1.5). Peptide hydroxamic acids have been shown to be inhibitors of metalloproteinase and some have been reported to have antibiotic, anticarcinogenic, and antiviral activities. Peptide hydroxamic adds may be prepared by solution and solid-phase methods using a variety of resins (Section 15.1.6). a-Aminoboronic acids may be prepared by several routes and are reported to be inhibitors of aminopepti-dases. Procedures have been developed for their incorporation into peptides (Section 15.1.7). 

Brorson SH (1998) Antigen detection on resin sections and methods for improving the immu-nogold labeling by manipulating the resin. Histol Histopathol 13 275-281... 

Y-D. Stierhof, H. Schwarz, M. Durrenberger, W. Villiger, and E. Kellenberger, Yield of Immunolabel Compared to Resin Sections and Thawed Cryosections, in Colloidal Gold Principles, Methods and Applications, Vol. 3 (ed. M. A. Hayat), Academic Press, New York, 1991, pp. 87-95. 

For AFM observations, the sample surface should be fairly smooth, with gently undulating hills corresponding to the structure of the surface. Although epoxy resin sections used for TEM (transmission electron microscope) have a smooth surface, they do not have sharp relief. There is a need to develop new methods to improve the resolution of surface structures... 

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