Residual type

Hexamethylenetetramine. Hexa, a complex molecule with an adamantane-type stmcture, is prepared from formaldehyde and ammonia, and can be considered a latent source of formaldehyde. When used either as a catalyst or a curative, hexa contributes formaldehyde-residue-type units as well as benzylamines. Hexa [100-97-0] is an infusible powder that decomposes and sublimes above 275°C. It is highly soluble in water, up to ca 45 wt % with a small negative temperature solubiUty coefficient. The aqueous solutions are mildly alkaline at pH 8—8.5 and reasonably stable to reverse hydrolysis. 

A prior distribution of the probabilities of the 20 amino acids at a particular position in a multiple alignment can be represented by a Dirichlet distribution, described in Section lI.E. That is, it is an expression of the values of the probabilities of each residue type r, where r ranges from 1 to 20, and E( i0,. = 1 ... 

Observed values for all residue types except glycine. Each point represents (j) and values for an amino acid residue in a well-refined x-ray structure to high resolution, (c) Observed values for glycine. Notice that the values include combinations of (j) and that are not allowed for other amino acids. (From J. Richardson, Adv. Prot. Chem. 34 174-175, 1981.1... 

In contrast to the 13C shifts, the 13C resonance frequencies are not indicative of residue type, which makes the assignment more demanding in comparison to the 13C , 15N, Hn correlation map. Nevertheless, the HN(CA)CO-TROSY scheme equipped with the selective 13C refocusing pulses during the 13C -13C/ transfer steps is able to provide 13C (i), 15N(i),... 

For the residue-type assignment of the cross peaks, the SH3 domain was expressed with specifically labeled glycine or arginine residues by using amino acid mixtures where only Gly and Arg were 15N-labeled. Again, yields for the labeled proteins were identical to those of the unlabeled product. Analysis of the corresponding [15N,1H]-HSQC spectra... 

Clearly, the potential to use spin labels as a means to reduce protein concentration for detection of protein-ligand interactions, given by the factor of 6582, is tremendous. The sixth-power dependence on electron-proton distance underlines the need to carefully design the residue type which is to be spin labeled. Residues that can be spin labeled include lysine, tyrosine, cysteine, histidine, and methionine [7, 14]. At least one residue of... 

In DSM-IV parlance, schizophrenia patients at this stage would most likely be diagnosed with residual type schizophrenia. 

Comparison of two series of dextran data shows the importance of considering the spectra in terms of specific residue type. One... 

The copper-binding sites in copper-containing proteins are characterized by three distinct classes. In Type-1, or blue copper centers, the copper is coordinated to at least two imidazole nitrogens from two histidyl residues and one sulfur from a cysteinyl residue. Type-1 coppers have small copper hyperfine couplings and a strong visible absorption in the Cu(ll) state. Type-2 or non-blue copper... 

Pilot Unit Test of Residue Type Catalysts on North Sea Atmospheric Residue... 

Wood, D.R., Reimherr, F.W., and Wender, RH. (1983) The use of L-deprenyl in the treatment of attention deficit disorder, residual type. Psychopharmacol Bull 19 627-629. 

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