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Renin inhibitors design/discovery

Data from Wood, J.M., et al. Structure-based design of aliskiren, a novel oraUy effective renin inhibitor, Biochem. Biophys. Res. Comm. 2003, 308, 698-705, and Kleinert, H.D., et al. Discovery of a peptide-based renin inhibitor with oral bioavail-abihty and efficacy Science 1992, 257, 1940-1943. [Pg.316]

Rahuel, J., Rasetti, V., Maibaum, J., Rueger, H., Goschke, R., et al. (2000) Structure-based drug design the discovery of novel nonpeptide orally active inhibitors of human renin. Chem. Biol. 7 493-504. [Pg.441]

See other pages where Renin inhibitors design/discovery is mentioned: [Pg.1]    [Pg.331]    [Pg.576]    [Pg.172]    [Pg.597]    [Pg.432]    [Pg.6]    [Pg.73]    [Pg.51]    [Pg.52]    [Pg.609]    [Pg.542]    [Pg.430]    [Pg.148]    [Pg.10]    [Pg.609]    [Pg.147]    [Pg.288]    [Pg.598]    [Pg.227]    [Pg.85]    [Pg.41]    [Pg.143]    [Pg.179]    [Pg.140]    [Pg.144]    [Pg.145]   
See also in sourсe #XX -- [ Pg.68 , Pg.69 , Pg.70 , Pg.71 , Pg.72 ]



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