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Relenza structure-based design

FIGURE 30.2 The first marketed drugs derived from structure-based design, (a) captopril (Capoten ), (b) dorzolamide (Trusopt ), (c) zanamivir (Relenza ), and (d) oseltamivir (Tamiflu ). [Pg.608]

Figure 7.16 Dihydrofolate reductase inhibitors methotrexate and Compound 7, (El-Hamamsy, M.H.R.L et al. Structure-based design, synthesis and preliminary evaluation of selective inhibitors of dihydrofolate reductase from Mycobacterium tuberculosis. Bioorg. Med. Chem. 2007, 15, 4552-4576.), neuraminidase inhibitor Relenza (zanamivir), and CCR5 blocker apiaviroc. Figure 7.16 Dihydrofolate reductase inhibitors methotrexate and Compound 7, (El-Hamamsy, M.H.R.L et al. Structure-based design, synthesis and preliminary evaluation of selective inhibitors of dihydrofolate reductase from Mycobacterium tuberculosis. Bioorg. Med. Chem. 2007, 15, 4552-4576.), neuraminidase inhibitor Relenza (zanamivir), and CCR5 blocker apiaviroc.
See other pages where Relenza structure-based design is mentioned: [Pg.609]    [Pg.609]    [Pg.733]    [Pg.251]    [Pg.1951]    [Pg.646]    [Pg.442]    [Pg.1109]   
See also in sourсe #XX -- [ Pg.451 ]

See also in sourсe #XX -- [ Pg.451 ]



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Design Bases

Design structures

Relenza

Structure based design

Structure designable

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