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Reformatsky reagents with aromatic halides

Couplings between Reformatsky reagents and aromatic halides are catalyzed by Ni(PPh3)4 " or Pd(PPh3)4, " " with DMF, NMP or HMPA being used as the essential cosolvents. While the Ni-cata-lyzed reaction can be applied to aromatic chlorides, bromides and iodides, the Pd-catalyzed reaction is useful only for iodides. Compatibility of the free carboxylic acid may especially be noted (equation 109). [Pg.454]


See other pages where Reformatsky reagents with aromatic halides is mentioned: [Pg.460]    [Pg.374]    [Pg.930]   
See also in sourсe #XX -- [ Pg.3 , Pg.454 ]

See also in sourсe #XX -- [ Pg.454 ]

See also in sourсe #XX -- [ Pg.3 , Pg.454 ]




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