Redox-responsive nanovehicles

Redox-responsive nanovehicles containing disulfide bonds have been reported. Biodegradable multiblock PUs bearing varied amounts of disulfide linkages were synthesized. The reducible PUs exhibited appropriate phase behavior and self-assembly properties. It was also found that the redox-sensitive PU micelles could rapidly enter tumor cells and can transport the encapsulated pacUtaxel effectively (Figure 8.9). The inhibition effects were controlled by adjusting the disulfide content in the polymeric backbone [96]. 

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