Red Sea Moses sole

Red Sea Moses sole Pardachinis marmoratus Pardaxins Peptides (33 amino acid residues) Sharks Affect taste shark withdraws... 

An example of pore-forming alpha helix acting via the barrel-stave models is the toxin pardaxin. This 33-residue peptide is found in the Red Sea Moses sole (a flatfish) and nsed to repel Sharks. It is found that this peptide binds to bilayer snrfaces and forms transmembrane pores consisting of 6 3 peptides. Remarkable is the efficiency... 

Lazarovici, P., Primor, N., and Moew, L.M. (1986) Purification and pore-forming activity of two hydrophobic polypeptides from the secretion of the Red Sea Moses sole Pardachirus marmoratus).]. Biol. Chem., 261, 16704-16713. 

Shai, Y, Fox, J., Caratsch, C., Shih, Y.L., Edwards, C., and Lazarovid, P. (1988) Sequencing and synthesis of pardaxin, a polypeptide from the Red Sea Moses sole with ionophore activity. FEES Lett., 242, 161-166. 

Pardaxins 33 Red Sea Moses sole and peacock sole of the western Pacific [92-94]... 

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