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Recognition selectivity, chromatographic studie

Sellergren B, Lespisto M, Mosbach K. Highly enantioselective and substrate-selective polymers obtained by molecular imprinting utilizing noncovalent interactions. NMR and chromatographic studies on the nature of recognition. J Am Chem Soc 1988 110 5853-5860. [Pg.426]

The molecular imprinting strategy can be applied for the recognition of different kinds of templates from small organic molecules to biomacromolecules as proteins. Some examples of separations investigated with MIP monoliths in CEC and LC are shown in Table 2. The influence of the imprinted monolithic phase preparation procedure and of the separation conditions on the selectivity and chromatographic efficiency have been widely studied [154, 157, 161, 166, 167, 192]. The performance of imprinted monoliths as chromatographic stationary phase has also been compared to that of the traditional bulk polymer packed column [149, 160]. It was shown that the monolithic phases yielded faster analyses and improved chiral separations. [Pg.66]

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See also in sourсe #XX -- [ Pg.128 ]



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