Rearrangements—Synthetic Reactions Not Liable to Retrosynthetic Analysis

Rearrangements—Synthetic Reactions Not Liable to Retrosynthetic Analysis 

A rearrangement reaction is a broad class of organic reactions where the carbon skeleton of a molecule is rearranged to give a strucmral isomer of the original molecule or a substituent moves from one atom to another, without or with elimination of carbon atom(s). Rearrangements are characterized by the spUt and formation of C-C and C-X bonds in the same process. 

Many rearrangements, such as Amdt-Eistert, Beckman or Hofmann rearrangements, have long been known to organic chemists. The industrial appUcation of some important rearrangements is outlined [1]. The mechanism and stereochemistry of these reactions are well defined. 

unjic and V. Petrovic Perokovic, Organic Chemistry from Retrosynthesis to Asymmetric Synthesis, DOI 10.1007/978-3-319-29926-6 8 

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