Reactions with Acrylamides

Solomon JJ, Fedky J, Mukai F, et al. 1985. Direct alkylation of 2 - deoxynucleosides and DNA following irLviiro reaction with acrylamide. Cancer Res 45 3465- 3470. 

Hydroxy-6-methyl-7,8,9,10-tetrahydrophenanthridine methio-dide is formed directly by the action of methyl iodide on the corresponding base.168 In an interesting reaction with acrylamide in methanolic hydrogen chloride, phenanthridine gives AT-(2-carbamoyl-ethyl)phenanthridinium chloride.288... 

I), other important alkaloids are used as amine reagents for Mannich synthesis. Thus, demethylatcd nicotine affords aminomethylation of hydrogen cyanide (460), employed in studies of the metabolic oxidation of nicotine, and anabasinc gives, by reaction with acrylamide, the readily polymerizable monomeric species 461, the polymeric derivative of which is. 50 times less toxic than the original anabasinc. ... 

The same is true for other polymer modification reactions with acrylamide derivatives especially cationic structures for the formation of cationic surface layers. Furthermore acrylamide derivates like methylenediacrylamide are used in various polymerisation reactions and have to be determined in polymer solutions. The polycations formed by a radical polymerization and their reaction products with polyanions (symplexes) have to be characterized when they are used in polymer modification or other fields. 

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