Reactions Performed in situ During Oxidation with IBX

Reactions Performed in situ During Oxidation With IBX 

Sometimes, enones—obtained by oxidation of allylic alcohols—suffer Diels-Alder reactions during oxidations with IBX.106a 

An enone obtained by IBX oxidation suffers an in situ intramolecular Diels-Alder reaction. Dess-Martin periodinane produces partial desilylation of the TIPS ether due to its slightly  

The oxidation of 1,2-ethylendiol with IBX leads to highly reactive gliceraldehyde that reacts in situ with PI13P = COjEt, resulting in a double Wittig olefination. 

Bagley et al. performed a number of pyrimidine and pyridine syntheses by condensing an inone—generated in situ by oxidation of a propargylic alcohol with IBX with amidines and p-aminocrotonate.108 

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