Reactions of the Carbaldehydes and Ketones

These carbonyl derivatives undergo the usual reactions associated with such compounds. The equilibrium of 1,8-naphthyridine-4-carbaldehyde with its hydrate has been studied.953 

Ethyl l-ethyl-7-formyl-4-oxo-1,4-dihydro- gave ethyl l-ethyl-4-oxo-7-phenyli-minomethyl-l,8-naphthyridine-3-carboxylate (44) (PhNH2, EtOH, reflux  

1 -Ethyl-6-fluoro-7-formyl- gave 1 -ethyl-6-fluoro-7-(hydroxyimino)methyl-4-oxo-1,4-dihydro-l,8-naphthyridine-3-carboxylic acid (45) (H2NOHHCl, pyridine, EtOH, reflux 86%).395 

3-Acetyl-2-methyl-1,8-naphthyridine gave 3-[ 1 -(benzoylhydrazono)ethyl]-1,8-naphthyridine (46) (BzHNNH2 %).516 

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