Reactions of substituents on carbon

In the great majority of examples, the reactions of substituents on carbon are those to be expected from a basic knowledge of organic chemistry. For example, cyclic amides (adjacent or vinylogous) are readily converted into the ring chloro derivative from which the chlorine atom may be displaced by a number of standard reactions (Scheme 1) <93H(36)2753>. Similar examples are cited elsewhere <85CPB3336, 94TL397). 

---