Reaction of a-Halo Acids with Benzyloxyamine

The synthesis of N-benzyloxyaspartic acid (154) from bromoacid (153) and benzyloxyamine was complicated by formation of the p-N-benzyloxyamide of malic acid (156) as by-product (164) from the P- 

Work at the Technical University of Gdansk has shown that N-benzyloxyamino acids are the best substrates for the synthesis of N-hydroxypeptides with hydroxylamine-protected oxygen because they crystallize well and, what is most important, the benzyl group may 

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