Rationale for Connecting Dissolution and Permeation Measurements

1 Improved in vivo/in vitro correlation for bioavailability screening of new 

3 Investigation of potential food effects on drug absorption. 

Improved In Vivo/In Vitro Correlation for Bioavailability Screening of New APIs 

However, for BCS class III (and IV), an in vitro/in vivo correlation of the dissolution result is often not possible, since dissolution is not rate limiting and other parameters cannot be detected in a dissolution setup. The latter therefore 

Investigation of Potential Food Effects on Drug Absorption 

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