Rapoport-Luebering shunt

The reaction catalyzed by PGK can be bypassed by the Rapoport-Luebering shunt (see Figure 21-8), thereby losing the gain of one ATP molecule. 

Fig. 10-27 Rapoport-Luebering shunt of giycoiysis. It is present in red blood cells of most mammals.

Figure 21 -8 Major glycolytic pathways of the erythrocyte. Substrates are in uppercase type, and enzymes are in parentheses. EMP, The Embden-Meyerhof pathway HMP hexose monophosphate pathway or pentose shunt RLC, the Rapoport-Luebering cycle ADP, adenosine diphosphate ATP, adenosine triphosphate NAD, nicotinamide-adenine dinudeotide NADH, reduced nicotinamide-adenine dinucleotide NADP, nicotinamide-adenine dinucleotide phosphate NADPH, reduced nicotinamide-adenine dinucleotide phosphate.The step from ribulose-5-phosphate, which is shown as being catalyzed by transketolase and transaldolase, is an abbreviation of this portion of the HMR...

---