Raman temporally fluctuating

Y, Verma, P., Kawata, S. and Inouye, Y. (2007) Temporal fluctuation of tip-enhanced Raman spectra of adenine molecules./. Phys. Chem. C, 111, 9460-9464. 

Moyer et al. [41] demonstrated that the two dimensionally domain size of nanocrystalline carbon was found to be in the order of 10 nm. Additional spectroscopic Raman measurements on nanocrystalline carbon adsorbed at separate isolated silver nanoparticles revealed temporal fluctuations in the peak intensities of the characteristic carbon bands and intermittent on/off behavior [41]. The SERS literature (e.g., [5, 10, 11]) frequently reports this phenomenon, called blinking. Most authors interpreted the blinking that only few nanocrystallites were involved. 

SERRS spectra of Fe-protoporphyrin IX adsorbed on Ag colloidal nanoparticles immobilized onto a polymer-coated glass slide were obtained at very low concentrations ". The spectra exhibit drastic temporal fluctuations on a time scale of seconds in both line frequency and intensity. This result is consistent with an approach to the single molecule limit. Sequences of spectra were analyzed in terms of an underlying continuum and of Raman peaks superimposed on this continuum. The statistical analysis of the spectrum intensity suggested that the main contribution to the intensity fluctuations arise from the continuum. It was found... 

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