Radiation and Biological Tissue

The radiolysis reaction of oxygenated aqueous solutions may be written, with the yields (G-values) for y-rays in parentheses [4]  

The formation of both HO and e is complete in 10 s with molecule formation from recombination or chemical reaction complete in 10 s. Both e and H react at diffustion controlled rates with oxygen giving superoxide  

Radical reaction leading to target lesions 10 to 10 Enzymatic repair of lesions Expression of cellular functions 

The vast majority of evidence implicates DNA as the primary radiation target and so the situation above can be summarized  

S = -aD-pD- [11] with S being the surviving fraction, D the dose, and n, a and are independent parameters. 

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