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Quinone metabolite identification

Zhao, S.X. et al. (2007) NADPH-dependent covalent binding of [3H] paroxetine to human liver microsomes and S-9 fractions identification of an electrophilic quinone metabolite of paroxetine. Chemical Research in Toxicology, 20 (11), 1649-1657. [Pg.377]

Incubation of morphine and [14C-methyl]-5-adenosylmethionine with rabbit liver homogenates resulted in the detection of 2-methoxymorphine as a minor metabolite/446 Oxidation at C-2 may also have occurred in rat brain homogenates with the tentative identification of morphine-2,3-quinone as a minor morphine metabolite/447 Morphine-N-oxide (266) and its 3-glucuronide have been isolated 448 from guinea pig urine after morphine adminstration, and a- and /3-dihydromorphine (264 and 265) were also established as metabolites by gc/ms of extracts of the urine of several species. [Pg.90]

See other pages where Quinone metabolite identification is mentioned: [Pg.348]    [Pg.255]    [Pg.369]    [Pg.97]    [Pg.148]    [Pg.676]    [Pg.193]    [Pg.784]    [Pg.79]    [Pg.73]    [Pg.222]    [Pg.254]   
See also in sourсe #XX -- [ Pg.421 ]



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Metabolite identification

Quinone metabolite

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