Quercetin-glycosides bioavailability

The bioavailibility of quercetin-glycosides from onions, containing mainly quercetin-p-glucosides, was superior to that of various quercetin glycosides from apples (containing a mixture of quercetin-(3-galactosides and P-xylosides) and of pure quercetin-3-mtinoside (major species in tea). The possible matrix effect of the foods remains unclear. 

Graefe EU, Wittig J, Mueller S, Riethling A, Uehleke B, Drewelow B, Pforte H, Jacobasch G, Derendorf H, Veit M. 2001. Pharmacokinetics and bioavailability of quercetin glycosides in humans. J Clin Pharmacol 41 492-499. 

Morand C, Manach C, Crespy V, Remesy C. Respective bioavailability of quercetin aglycone and its glycosides in a rat model. Biofactors 2000 12 169-174. 

Until recently, the extent of absorption and bioavailability of flavonoids was somewhat unclear. Studies with ileostomy patients have shown that humans can absorb significant amounts of quercetin and that glycosides can be absorbed from the small intestine. Absorption of quercetin glucosides was... 

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