Pyrrolo-pyridines nitration

Pyrrolo[3,4-d]pyridazinium salts, 2,3-dimethyl-synthesis, 4, 291 Pyrrolo[ 1,2-6]pyridazinones oxidation, 4, 298 Pyrrolo[2,3-6]pyridine, 1-acetyl-cycloaddition reactions, 4, 509 Pyrrolo[2,3-6]pyridine, 3-bromo-nitration, 4, 505... 

Pyrrolo[2,3-6]pyridine, 2,3-dihydro-electrophilic substitution, 4, 503 nitration, 4, 512 synthesis, 4, 520... 

Transformations involving dihydro derivatives of the pyrrolopyridines have been reported as useful methods for achieving substitution at positions of the ring that do not readily react directly. For example, substituents have been introduced into compound (59), which can be subsequently dehydrogenated to the pyrrolopyridine derivative. Scheme 17 shows that from transformations beginning with the nitration of compound (59), 5-nitro-l//-pyrrolo[2,3-6]pyridine (64) and 5-amino-1 /7-pyrrolo[2,3-6]pyridine (65) can be obtained <59JA743>. 

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