Pyridine, reactions with—continued reduction

Darr and Poliakoff conducted one of the first studies where SC-CO2 was used in a two-stage continuous reaction and purification process to form pure organo-metallic products. The ds-W(CO)4(pyridine)2 or novel c/ -W(CO)4(3,5 lutidine)2 were formed in a continuous flow reactor at 488 K and were then removed from solution via precipitation, with a second flow of CO2 used to remove the excess solvent and reactant for reclamation and recycle. The benefits of this system, aside from the production of novel materials, include reduction of organic solvent consumption, decrease in number of stages and time, and production of 100% purity product. 

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