Pyrazoles, synthesis and properties

Acetylenecarboxylic esters, reactions with nitrogen-containing heterocycles, 23, 263 Acetylenic derivatives of pyrazoles, synthesis and properties of, 82, 1 Acetylenic esters, synthesis of heterocycles through nucleophilic additions to, 19,297 Acid-catalyzed polymerization of pyrroles and indoles, 2, 287... 

One of the practically important synthetic pathways to aryl-containing pyrazole derivatives is a reaction of oufi-unsaturatcd ketones with dipolar molecules or 1,2-binucleophiles. There are dozens of stereotypical publications on this topic and in this chapter we will not cite all existing references related to the synthesis and properties of pyrazole derivatives based on unsaturated carbonyl compounds but will cover the most general and some specific examples as well as mechanisms. 

S. F. Vasilevsky Synthesis and properties of acetylenic derivatives of pyrazoles 2002AHC1... 

Vasilevsky, S.F., Tretyakov, E.V. and Elguero, J. (2002) Synthesis and properties of acetylenic derivatives of pyrazoles, in Advances in Heterocyclic Chemistry, vol. 82 (ed. A.R. Katritzky), Elsevier, New York-London, pp. 1-99. 

Yang, G. and Raptis, R.G. (2003) Synthesis, structure and properties of tetrameric gold(I) 3,5-di-tert-butyl—pyrazolate. Inorganica Chimica Acta, 352, 98—104. 

A large body of work with particular reference to the mimicry of mononuclear zinc enzymes has utilized tris(pyrazolyl)borate ligands. This ligand class offers a facial coordination mode of three pyrazole A-donors and can be functionalized in the three and five positions on the rings to increase steric bulk and vary the electronic properties of the ligand. The synthesis and complex formation with these ligands has been extensively reviewed.2,21 219... 

In previous work (85MI1 87AHC319), the synthesis and chemistry of pyrazolopyridines and pyrazolopyrimidines was surveyed. This chapter reports synthetic approaches to other aromatic 10 tt electron systems containing a pyrazole moiety, as well as the systems main chemical and physicochemical properties. 

Poly(pyrazolyl)borate complexes of Sn(II) and Pb(II) 92SL469. Synthesis, structure, and properties of vicinal hydroxy-, mercapto-, and hydroselenoaldimines of the pyrazole series 92MI22. 

A large body of information on the methods of synthesis, application, structure, and properties of all known five-membered nitroazoles - pyrazoles, imidazoles, triazoles, tetrazoles, oxazoles, isoxazoles, oxadiazoles, thiazoles, isothiazoles, thiadiazoles, selenazoles, selenadiazoles, and their benzo analogs - indazoles, benzimidazoles, benzoxazoles, benzisoxazoles, benzoxadiazoles, benzothiazoles, benzoisothiazoles, benzothiadiazoles, benzotriazoles, benzoselenazoles, and ben-zoselenadiazoles has been systematized, summarized, and critically discussed in this monograph. 

Sosnovskikh VYa, Barabanov MA, Usachev Bl, Irgashev RA, Moshkin VS (2005) Synthesis and some properties of 6-di(tri)lluoromethyl- and 5-di(tri)lluoroacetyl-3-methyl-l-phenylpyrano[2,3-c]pyrazol-4(lfl)-ones. Russ Chem Bull (Engl Transl) 54 2846-2850... 

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