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2-Pyrazinamine analogue

Dibromo-2-pyrazinamine (123, R = Br) gave 3-benzyloxy-5-bromo-2-pyrazinamine (123, R = OCH2Ph) (PHCH2ONa, PhCH2OH, reflux, 4 h 51%) 661 also analogues likewise.661 Also other examples.1012 1198... [Pg.161]

Pyrazinamine 4-oxide (292) gave 3-azido-2-pyrazinamine (293) (Me3SiN3, Et2NCOCl, MeCN, reflux, A, 18 h >95%) 46 analogues such as 2-azido-3,5-(>95%),46 2-azido-5,6- (85%),46 and 2-azido-3,6-diphenylpyrazine (294) (67%)231 were made similarly. [Pg.237]

Pyrazinamine (27, R = H) gave 3-benzyl-2-pyrazinamine (27, R = CH2Ph) (pre-fonned PhCHjLi, THF, 0°C, N2, 1 h 32%) 2-acetamidopyrazine (28, R = H) gave 2-acetamido-3-benzylpyrazine (28, R = CH2Ph) (37%) and other analogues were made similarly without added oxidant. ... [Pg.81]

See other pages where 2-Pyrazinamine analogue is mentioned: [Pg.81]    [Pg.96]    [Pg.143]    [Pg.96]    [Pg.143]   
See also in sourсe #XX -- [ Pg.286 ]

See also in sourсe #XX -- [ Pg.286 ]



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