Pteroylglutamic acid preparation

A concentrated pteroylglutamic acid (PGA) solution (1 mg/ml) is prepared with crystalline PGA dissolved in 20% (v/v) ethanol/water. The pH is adjusted with 0.1 N NaOH to pH 10-11 to dissolve the PGA, 0.06 N H2S04 is then used to readjust the pH to 7.0. Appropriate dilutions... 

Another isocytosine analogue of pteroylglutamic acid which has been prepared is (LXIII), as well as its 7,10-methenyl derivative (LXIV) [386]. 

Multivitamin preparations. Most water-soluble vitamins are polarographically active and can be determined in simple preparations without any difficulties. Difficulty is given, however, with complex multivitamin preparations. In a preparation containing in I O g (in addition to fillers) 2500 I.U. of vitamin A, 200 I.U. of vitamin D, 1 mg of vitamin Bj, T5 mg of vitamin Bg, 1 /ag of vitamin B 2> mg of pteroylglutamic acid, 0-5 mg of calcium pantothenate, 10 mg of niacinamide, 37-5 mg of vitamin C, 1 mg of vitamins E and 0-2 mg of vitamins K, the analyses were carried... 

---