Pseudoceratina ceratinamine

Psammaplysin E (84), ceratinamine (85), and molokaiamine (86) from the sponge Pseudoceratina purpurea exhibit potent cytotoxicity against P-388 murine leukemia cells with IC50 values of 2.1, 3.4, and 2.1 pg/ml, respectively [74]. Recently, the related waianaeamines have been isolated from an undescribed verongid sponge from Molokai Island [75]. 

Tsukamoto S, Kato H, Hirota H, Fusetani N (1996) Ceratinamine An Unprecedented Antifouling Cyanoformamide from the Marine Sponge Pseudoceratina purpurea. J Org Chem 61 2936... 

Tsukamoto, S., Kato, H., Hirota, H., and Fusetani, N., Ceratinamine an unprecedented antifouling cyanoformamide from the marine sponge Pseudoceratina purpurea, J. Org. Chem., 61, 2936, 1996. 

Schoenfeld, R.C. and Ganem, B. (1998) SynAesis of ceratinamine and molokaiamine antifouhng agents from Ae marine sponge Pseudoceratina purpurea. Tetrahedron Lett., 39,4147-4150. 

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